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<\/span><\/div><\/div>Dr. John M. Lindner<\/h2><\/div>Head of Immunology Discovery & Head of Research USA<\/p>\n<\/div>
<\/i>lindner@bio.mx<\/a><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/i>+49 6221 426 11 28<\/a><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>Acknowledgements<\/strong><\/h3><\/div>From 2023 Head of Immunology Discover and Head of Research USA
2018 – 2023:<\/strong> BioMed X Group Leader
2014 – 2018:<\/strong> Postdoc, Novartis Institutes for Biomedical Research, Basel, Switzerland
2013 – 2014:<\/strong> Postdoc, Freiburg Institute of Advanced Studies, Freiburg, Germany
2007 – 2013:<\/strong> PhD, University of Freiburg, Germany<\/p>\n<\/div><\/div><\/div>Published Articles<\/strong><\/h3><\/div>Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis.<\/a><\/p>\nH3K27M neoepitope vaccination in diffuse midline glioma induces B and T cell responses across diverse HLA loci of a recovered patient. <\/a><\/p>\nT-FINDER: A highly sensitive, pan-HLA platform for functional T cell receptor and ligand discovery. <\/a><\/p>\nDisease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE. <\/a><\/p>\nLoss of immune tolerance to IL-2 in type 1 diabetes. <\/a><\/p>\nHuman Memory B Cells Harbor Diverse Cross-Neutralizing Antibodies against BK and JC Polyomaviruses. <\/a><\/p>\nAntigen Extraction and B Cell Activation Enable Identification of Rare Membrane Antigen Specific Human B Cells. <\/a><\/p>\nCutting edge: The transcription factor Bob1 counteracts B cell activation and regulates miR-146a in B cells.
\n<\/a><\/p>\nPublisher Correction: Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA <\/a>vaccination in human SLE. <\/a><\/p>\nA C-terminal acidic domain regulates degradation of the transcriptional coactivator Bob1. <\/a><\/p>\nSynthetic Standards Combined With Error and Bias Correction Improve the Accuracy and Quantitative Resolution of Antibody Repertoire Sequencing in Human Na\u00efve and Memory B Cells. <\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div>![](\"https:\/\/smaac.dev\/biomedx\/wp-content\/uploads\/2025\/03\/211021-Team-IAA-web-picture.jpg\" "\\"211021-Team-IAA-web-picture\\"")
<\/span><\/div><\/div><\/div><\/div><\/div>Team IAA<\/span><\/a><\/div>- <\/i><\/span>Taga Lerner<\/div><\/li>
- <\/i><\/span>Theresa Shmid<\/div><\/li>
- <\/i><\/span>
Head of Immunology Discovery & Head of Research USA<\/p>\n<\/div>
lindner@bio.mx<\/a><\/span><\/p>\n<\/div><\/div><\/div><\/div> +49 6221 426 11 28<\/a><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div> From 2023 Head of Immunology Discover and Head of Research USA Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis.<\/a><\/p>\n H3K27M neoepitope vaccination in diffuse midline glioma induces B and T cell responses across diverse HLA loci of a recovered patient. <\/a><\/p>\n T-FINDER: A highly sensitive, pan-HLA platform for functional T cell receptor and ligand discovery. <\/a><\/p>\n Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE. <\/a><\/p>\n Loss of immune tolerance to IL-2 in type 1 diabetes. <\/a><\/p>\n Human Memory B Cells Harbor Diverse Cross-Neutralizing Antibodies against BK and JC Polyomaviruses. <\/a><\/p>\n Antigen Extraction and B Cell Activation Enable Identification of Rare Membrane Antigen Specific Human B Cells. <\/a><\/p>\n Cutting edge: The transcription factor Bob1 counteracts B cell activation and regulates miR-146a in B cells. Publisher Correction: Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA <\/a>vaccination in human SLE. <\/a><\/p>\n A C-terminal acidic domain regulates degradation of the transcriptional coactivator Bob1. <\/a><\/p>\n Synthetic Standards Combined With Error and Bias Correction Improve the Accuracy and Quantitative Resolution of Antibody Repertoire Sequencing in Human Na\u00efve and Memory B Cells. <\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div>Acknowledgements<\/strong><\/h3><\/div>
2018 – 2023:<\/strong> BioMed X Group Leader
2014 – 2018:<\/strong> Postdoc, Novartis Institutes for Biomedical Research, Basel, Switzerland
2013 – 2014:<\/strong> Postdoc, Freiburg Institute of Advanced Studies, Freiburg, Germany
2007 – 2013:<\/strong> PhD, University of Freiburg, Germany<\/p>\n<\/div>Published Articles<\/strong><\/h3><\/div>
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